Fig. 2

OGN was associated with viability and tumorigenic ability of colorectal cancer cells. a1, The pattern of OGN in the normal human colon mucosal epithelial cells (NCM460) and colon cancer cell lines. Efficiency of OGN over-expression in cancer cell lines was measured by western blot. a2, Influence of OGN expression on viability of cancer cells was measured by CCK-8 assay. * indicates p value less than 0.05 VS. control cells. Wound healing assay (b, c) and cell invasion (d, e). The results are expressed as the mean ± SD of three independent experiments