Fig. 5

Snail is required for CXCL5/CXCR2 axis-triggered EMT. a The expression profiles of ZEB1, Twist, Slug and Snail in the stable transfected cells based on western blot analysis. The knockdown of Snail with small interfering RNA reversed the CXCL5/CXCR2 axis-triggered EMT phenotype in the NPC cells as revealed by a western blot analysis and (b) cellular morphology. c The knockdown of Snail abolished the invasive ability of the NPC cells that was induced by the CXCL5/CXCR2 axis. These experiments were repeated at least three times. Error bars, mean ± SD. **P < 0.01, ***P < 0.001