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Table 1 Clinicopathological correlation of CXCL5 expression and CXCR2 expression in NPC

From: The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

 

All patients

CXCL5

CXCR2

n = 107(%)

High (n = 44)

Low (n = 63)

P

High (n = 52)

Low (n = 55)

P

Age (year)

 < 50

68(63.6)

27

41

0.694

30

38

0.221

 ≥ 50

39(36.4)

17

22

22

17

Gender

 Male

84(78.5)

35

49

0.827

37

47

0.072

 Female

23(21.5)

9

14

15

8

Tumor classification

 T1–2

59(55.1)

22

37

0.372

27

32

0.515

 T3–4

48(44.9)

22

26

25

23

Nodal classification

 N0–1

78(72.9)

26

52

0.007

33

45

0.033

 N2–3

29(27.1)

18

11

19

10

Clinical classification

 I-II

44(41.1)

14

30

0.102

20

24

0.587

 III-IVb

63(58.9)

30

33

32

31

Local-regional recurrence

 No

90(84.1)

35

55

0.280

46

44

0.231

 Yes

17(15.9)

9

8

6

11

Distant metastasis

 No

85(79.4)

32

53

0.055

37

48

0.039

 Yes

22(20.6)

12

10

15

7

Progression

 No

70(65.4)

24

46

0.048

32

38

0.412

 Yes

37(34.6)

20

17

20

17

  1. Progression is defined as local-regional recurrence and/or distant metastasis after initial treatment. Statistical significance (P < 0.05) is shown in bold and italic