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Table 2 Cox proportional hazard regression analyses for 10-year OS and 10-year DMFS

From: The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

Prognosis

Wald

P

Exp(B)

95% CI for Exp(B)

Lower

Upper

OS

 Age(year) ≥50 vs.<50

1.577

0.215

1.643

0.788

3.319

 Gender Female vs. Male

3.298

0.081

2.506

0.907

6.387

 Histological type U vs. D

0.441

0.526

0.745

0.253

2.479

 T classification T2–4 vs. T1

9.309

0.003a

3.568

1.521

6.517

 N classification N1-3vs. N0

12.505

0.001a

2.389

1.543

4.228

 Clinical classification II-IVb vs. I

6.218

0.014a

0.487

0.119

0.668

 CXCL5 expression High vs. Low

4.885

0.027

1.960

1.079

3.560

 CXCR2 expression High vs. Low

1.295

0.255

0.691

0.365

1.307

DMFS

 Age(year) ≥50 vs.<50

1.267

0.234

2.137

0.802

4.304

 Gender Female vs. Male

3.137

0.091

3.267

0.798

13.223

 Histological type U vs. D

0.702

0.564

0.523

0.158

2.694

 T classification T2–4 vs. T1

3.236

0.079a

2.413

0.903

6.446

 N classification N1-3vs. N0

6.533

0.004a

2.578

1.131

6.327

 Clinical classification II-IVb vs. I

2.786

0.095a

0.413

0.251

1.099

 CXCL5 expression High vs. Low

5.169

0.023

2.740

1.149

6.532

 CXCR2 expression High vs. Low

1.700

0.192

1.879

0.728

4.849

  1. a adjusted P-values < 0.017 were considered statistically significant
  2. OS overall survival, DMFS distant metastasis-free survival, sCXCL5 serum CXCL5, D differentiated non-keratinized carcinoma, U undifferentiated non-keratinized carcinoma, CI confidence interval