From: Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis
Group
PBS
N-S
sh-HMGB1-S
N-S + EP
rhHMGB1 (150Â ng/ml)
Numbers of animals
4
Lung nodules
0/4 (0%)
3/4 (75%)
1/4 (25%)
Lymph nodes
2/4 (75%)