Fig. 4

UBE2CP3 promoted angiogenesis in vivo. a CAM angiogenesis assays showed that when injected with HCC cells overexpressing UBE2CP3, the density of new chick embryo vessels increased. b Chick embryos injected with UBE2CP3 knockdown cells had decreased new vessel density. c CD31/PAS double-staining results showed that mice injected with cells overexpressing UBE2CP3 had higher EV density in the tumor tissue than those injected with Lv-control cells. d Mice injected with UBE2CP3 knockdown cells had lower EV density in the tumor tissue than those injected with the sh-control cells