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Table 1 Correlation among UBE2CP3, EV density and clinicopathological parameters of HCC patients in cohort1

From: Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma

 

UBE2CP3

EV

Low(n)

High(n)

P

Low(n)

High(n)

P

All cases

26

22

 

31

17

 

Age(year)

 >=55

16

13

0.863

17

12

0.286

 <55

10

9

 

14

5

 

Sex

 Male

21

21

0.274

28

14

0.732

 Female

5

1

 

3

3

 

Edmondson grade

 I~II

20

13

0.184

21

12

0.839

 III~IV

6

9

 

10

5

 

Tumor invasiona

 T1~T2

15

7

0.037*

16

6

0.193

 T3~T4

9

15

 

13

11

 

Cirrhosis

 Without

17

11

0.281

18

10

0.959

 With

9

11

 

13

7

 

Tumor number

 Single

26

14

0.003**

29

11

0.031*

 Multiple

0

8

 

2

6

 

Tumor size,cm

 <=10

20

12

0.101

24

8

0.033*

 >10

6

10

 

7

9

 

Mortality

 Survive

15

5

0.014*

16

4

0.059

 Die

11

17

 

15

13

 
  1. Abbreviations: EV endothelial vessel, UBE2CP3 ubiquitin conjugating enzyme E2 C pseudogene 3. *P < 0.05, ** P < 0.01
  2. aRemarks: 2 records of tumor invasion were missing