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Table 1 Correlation among UBE2CP3, EV density and clinicopathological parameters of HCC patients in cohort1

From: Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma

  UBE2CP3 EV
Low(n) High(n) P Low(n) High(n) P
All cases 26 22   31 17  
Age(year)
 >=55 16 13 0.863 17 12 0.286
 <55 10 9   14 5  
Sex
 Male 21 21 0.274 28 14 0.732
 Female 5 1   3 3  
Edmondson grade
 I~II 20 13 0.184 21 12 0.839
 III~IV 6 9   10 5  
Tumor invasiona
 T1~T2 15 7 0.037* 16 6 0.193
 T3~T4 9 15   13 11  
Cirrhosis
 Without 17 11 0.281 18 10 0.959
 With 9 11   13 7  
Tumor number
 Single 26 14 0.003** 29 11 0.031*
 Multiple 0 8   2 6  
Tumor size,cm
 <=10 20 12 0.101 24 8 0.033*
 >10 6 10   7 9  
Mortality
 Survive 15 5 0.014* 16 4 0.059
 Die 11 17   15 13  
  1. Abbreviations: EV endothelial vessel, UBE2CP3 ubiquitin conjugating enzyme E2 C pseudogene 3. *P < 0.05, ** P < 0.01
  2. aRemarks: 2 records of tumor invasion were missing