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Table 2 Correlation among UBE2CP3, CD31 mRNA and clinicopathological parameters of HCC patients in cohort 2

From: Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma

  UBE2CP3 CD31 mRNA
Low(n) High(n) P Low(n) High(n) P
All cases 22 24   29 17  
Age(year)
 >=55 13 14 0.958 17 10 0.989
 <55 9 10   12 7  
Sex
 Male 16 20 0.384 21 15 0.376
 Female 6 4   8 2  
Edmondson grade
 I~II 14 12 0.351 15 11 0.391
 III~IV 8 12   14 6  
Tumor invasion
 T1~T2 14 7 0.019* 16 5 0.090
 T3~T4 8 17   13 12  
Cirrhosis
 Without 13 12 0.536 18 7 0.170
 With 9 12   11 10  
Tumor number
 Single 21 16 0.014* 27 10 0.015*
 Multiple 1 8   2 7  
Tumor size,cm
 <=10 15 11 0.127 20 6 0.026*
 >10 7 13   9 11  
  1. The median expression level was used as the cut off. Low expression of UBE2CP3 in 22 patients was classified as values below the 50th percentile. High UBE2CP3 expression in 24 patients was classified as values at or above the 50th percentile.
  2. Abbreviations: EV endothelial vessel, UBE2CP3 ubiquitin conjugating enzyme E2 C pseudogene 3. *P < 0.05, ** P < 0.01