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Table 2 Correlation among UBE2CP3, CD31 mRNA and clinicopathological parameters of HCC patients in cohort 2

From: Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma

 

UBE2CP3

CD31 mRNA

Low(n)

High(n)

P

Low(n)

High(n)

P

All cases

22

24

 

29

17

 

Age(year)

 >=55

13

14

0.958

17

10

0.989

 <55

9

10

 

12

7

 

Sex

 Male

16

20

0.384

21

15

0.376

 Female

6

4

 

8

2

 

Edmondson grade

 I~II

14

12

0.351

15

11

0.391

 III~IV

8

12

 

14

6

 

Tumor invasion

 T1~T2

14

7

0.019*

16

5

0.090

 T3~T4

8

17

 

13

12

 

Cirrhosis

 Without

13

12

0.536

18

7

0.170

 With

9

12

 

11

10

 

Tumor number

 Single

21

16

0.014*

27

10

0.015*

 Multiple

1

8

 

2

7

 

Tumor size,cm

 <=10

15

11

0.127

20

6

0.026*

 >10

7

13

 

9

11

 
  1. The median expression level was used as the cut off. Low expression of UBE2CP3 in 22 patients was classified as values below the 50th percentile. High UBE2CP3 expression in 24 patients was classified as values at or above the 50th percentile.
  2. Abbreviations: EV endothelial vessel, UBE2CP3 ubiquitin conjugating enzyme E2 C pseudogene 3. *P < 0.05, ** P < 0.01
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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