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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance

Fig. 2

Schematic of possible mechanisms of reactive oxygen species (ROS)-induced tumor progression. Excessive intracellular ROS in cancer cells can regulate growth factor receptors, cell cycle regulators, and mitogen-activated protein kinase (MAPK) signaling that contribute to cancer progression by promoting cell proliferation, survival, migration, invasion, and angiogenesis

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