Fig. 2From: The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistanceSchematic of possible mechanisms of reactive oxygen species (ROS)-induced tumor progression. Excessive intracellular ROS in cancer cells can regulate growth factor receptors, cell cycle regulators, and mitogen-activated protein kinase (MAPK) signaling that contribute to cancer progression by promoting cell proliferation, survival, migration, invasion, and angiogenesisBack to article page