Journal of Experimental & Clinical Cancer Research

Table 2 Correlation of the expression of ALK fusion gene detected by RT-qPCR and FISH

From: 5′/ 3′ imbalance strategy to detect ALK fusion genes in circulating tumor RNA from patients with non-small cell lung cancer

Cases	RT-qPCR^a		FISH		Pathol.
Cases	expression value	+/−	+/−	%	Pathol.
021	33.6	+	+	18	A
124	439.1	+	+	68	AS
065	123	+	+	38	A
075	263	+	+	53	AS
184	58.9	+	+	23	A
046	49	+	+	20	A
089	67.9	+	+	27	A
102	759.9	+	+	90	A
018	132.35	+	+	41	A
068	236.5	+	+	49	A
135	468.3	+	+	73	A
006	523.1	+	+	77	A
029	536.2	+	+	79	A
173	458.2	+	+	70	AS
084	369.1	+	+	61	A
003	786.2	+	+	92	A
044	865.4	+	+	93	A
148	385.2	+	+	63	A
039	46.2	+	+	20	A
017	56.8	+	+	23	A

NOTE: +, positive; −, negative; Pathol., pathology; A, adenocarcinoma; AS, adenosquamous carcinoma; ^aExpression in 3′ portion of ALK mRNA relative to 5′ portion and expression value = 2^-△△CT = 2^{-[(CT(ALK E20)- CT(ACTB))-(CT(ALK E3)-CT(ACTB))]}

Back to article page

ISSN: 1756-9966

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com