Fig. 4
From: MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma
TFAP2C suppresses PDAC cell migration and invasion. a TFAP2C mRNA levels in six pancreatic cell lines; b TFAP2C protein levels in six pancreatic cell lines; c TFAP2C overexpression decreased cell migration and invasion, while TFAP2C knockdown using siRNA significantly increased cell migration and invasion; d TFAP2C negatively regulated Ras, c-Myc, p27, Snail, ZEB1 and N-Cadherin protein levels and up-regulated the p21 level in AsPC-1 and T3M4 cells. e The relative intensity of the grayscale band values revealed the changes with TFAP2C overexpression or knockdown in PDAC cells. The data are presented as the means ± SD (Student’s t-test; *, P < 0.05)