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Table 2 NCV studies in clinical development trial

From: The perfect personalized cancer therapy: cancer vaccines against neoantigens

Clinical trial

Cancer

Intervention

vaccine

status

NCT01885702

Colorectal Cancer

DC vaccination

DC

Active, not recruiting

NCT02632019

Biliary tract tumor

DC vaccination and gemcitabine

DC

Unknown status

NCT02956551

Lung cancer

DC vaccination

DC

Not yet recruiting

NCT03122106

Pancreatic Cancer

Neoantigen DNA vaccine with electroporation

DNA

Recruiting

NCT03199040

Triple Negative Breast Cancer

Neoantigen DNA vaccine and Durvalumab

DNA

Not yet recruiting

NCT01970358

Melanoma

Peptides with Poly-ICLC

peptide

Active, not recruiting

NCT03068832

Pediatric Brain Tumor

Peptide vaccine with Poly ICLC

peptide

Not yet recruiting

NCT02287428

Glioblastoma

NeoAntigen Vaccine and Radiation Therapy

peptides

Active, not recruiting

NCT02897765

Many

NEO-PV-01 and Nivolumab

peptides

Recruiting

NCT02950766

Kidney Cancer

Drug: NeoVax|Drug: Ipilimumab

peptides

Not yet recruiting

NCT03166254

Lung Cancer

Long peptide with Poly ICLC and Pembrolizumab

Peptides

Not yet recruiting

NCT03219450

Lymphocytic Leukemia

NeoVax with Cyclophosphamide

peptides

Not yet recruiting

NCT03359239

Urothelial Bladder Cancer

Peptides with Poly ICLC and Atezolizumab

peptides

Not yet recruiting

NCT03361852

Follicular Lymphoma

Neo Vax and Rituximab

peptides

Not yet recruiting

NCT03380871

Lung Cancer

NEO-PV-01 Pembrolizumab Carboplatin Pemetrexed

peptides

Not yet recruiting

NCT03422094

Glioblastoma

NeoVax and Nivolumab Ipilimumab

Peptides

Not yet recruiting

NCT03289962

Many

Drug: RO7198457|Drug: Atezolizumab

RNA

Recruiting

NCT02992977

many

AutoSynVax TM vaccine

HSP Peptides

Active, not recruiting