Fig. 1
From: Role of metabolism in cancer cell radioresistance and radiosensitization methods
The biological effects of radiation and the mechanism of radiation resistance. The outer ring indicates the biological effects of IR under normal conditions. The abnormal alterations of these effects will further induce the occurrence of radiation resistance. The inner ring indicates the mechanism of radiation resistance and the biological changes in the occurrence of radioresistance. These abnormal changes are the important reasons for treatment failure of cancer patients