Role of metabolism in cancer cell radioresistance and radiosensitization methods

Table 1 Metabolism-associated targets in radioresistance and the radiosensitization methods

Items	Targets	Radiosensitizer	Reference
Glycose metabolism	GLUT1	Apigenin,WZB117	[77, 81]
	MCT1	CHC	[94]
	LDHA	FX-11, miR-34	[95, 100, 101]
	PKM2	miR-133, DADA	[145, 147]
	HK2	2-DG	[149, 150]
	HIF	Chetomin, KNK437, 2-ME2,	[121, 123, 124]
		Barberin, NVP-BEZ235, miR-216a	[128, 129, 140]
		NSC74859, Stattic, Docetaxel	[130,131,132,133]
		miR-21, miR-124, miR-144	[138, 139]
Mitochondrial metabolism	Oxidative stress	Sorafenib, Ceremides, DADA	[147, 158, 159]
Mitochondrial metabolism	MMP	PD98059, HDIs, Paclitaxel	[164,165,166]

ISSN: 1756-9966