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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation

Fig. 1

Expressions of the LOX family members in HCC cells under diverse stiffness stimulation. (a) mRNA expression levels of LOX, LOXL1, LOXL2, LOXL3 and LOXL4 in MHCC97H and Hep3B cells grown on 6 KPa (L), 10 KPa (M), and 16 KPa (H) stiffness substrate. (b) (i, ii) The protein expression level of LOX, LOXL1, LOXL2, LOXL4 in MHCC97H and Hep3B cells grown on 6 KPa (L), 10 KPa (M), and 16 KPa (H) stiffness substrate. LOXL3 was not detected at the protein level. Error bar represents SEM, *p < 0.05, **p < 0.01 and ***p < 0.001

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