Fig. 2

Morphological changes of HCC cells under different stiffness stimulation and the expression of LOXL2 and c-JUN in HCC tissue with different liver stiffness backgrounds. (a) Morphology of MHCC97H and Hep3B cells cultured on 6 kPa, 10 kPa, and 16 kPa stiffness substrates. (b) (i) The expression levels of LOXL2 in HCC tissues with normal liver stiffness backgrounds (groups L), medium liver stiffness backgrounds (group M) and high liver stiffness backgrounds (group H). (ii) The expression levels of c-JUN in HCC tissues with different liver stiffness backgrounds. Error bar represents SEM, *p < 0.05