Fig. 6

HSP27 and DHT affected the tumor formation and metastasis in vivo using MDA-MB-453 cells. The effect of DHT and HSP27 knock-down on xenograft tumors growth and formation was described by tumor volume curve (a). Images of tumors removed from the mice (b). HE staining, immunohistochemistry staining for HSP27 and Ki67, and TUNEL staining were carried out on xenograft tumors (c). Representative images of liver with cancer cells invasion (d)