Fig. 4

miR-93 exerted oncogenic functions in PCa. a. MTS assay showed that the proliferation rate of PC3 and DU145 cells was significantly repressed after silencing of miR-93, while the cell proliferation was dramatically accelerated following overexpression of miR-93. b. Representative photographs of the colony formation assay showed miR-93 mimics promoted PCa cell survival and proliferation. c-d. Transwell assay showed high expression of miR-93 promoted PCa cell migration (C) and invasion (D). e-f. Column figures using data from Transwell assay showed high expression of miR-93 promoted PCa cell migration (E) and invasion (F) in two PCa cell lines. g. Western blot results showed the regulatory functions of miR-93 expression on epithelial-mesenchymal markers in DU145 cells. *, P < 0.01; **, P < 0.01