Table 1 The IC50 of APG-115 in six gastric cancer cell lines with different p53 status
Cell lines | p53 Status | IC50 for APG-115 (nM) |
|---|---|---|
AGS | Wild-type | 18.9 ± 15.6 |
MKN45 | Wild-type | 103.5 ± 18.3 |
BGC-823 | deletion | > 10,000 |
SGC-7901 | deletion | > 10,000 |
N87 | Mutation | > 10,000 |
NUGC-3 | Mutation | > 10,000 |