Skip to main content

Table 1 General characteristics and baseline clinicopathological features of DLBCL patients

From: Serum miR-22 as potential non-invasive predictor of poor clinical outcome in newly diagnosed, uniformly treated patients with diffuse large B-cell lymphoma: an explorative pilot study

Variables

DLBCL n = 36 (%)

Age median (range)

62 (23–83)

Gender males/females

20/16

Ann-Arbore stage

I-II

9 (25)

III-IV

27 (75)

IPI

Low (0–1)

8 (22)

Medium (2–3)

15 (42)

High (4–5)

13 (36)

LDH

Normal

18 (50)

High

18 (50)

Ki-67

<  70%

15 (42)

≥ 70%

21 (58)

Cell of origin

GC

22 (61)

Non-GC

10 (28)

NE

4 (11)

Translocations (§)

None

10 (28)

Single

10 (28)

Double hit

4 (11)

NE

12 (33)

Response to treatment (^)

ORR

27 (84)

CRR

24 (75)

Primary refractory

5 (15)

  1. NE: not evaluable; ORR: overall response rate, CRR: complete remission rate; GC: germinal-center;
  2. (§) Translocations evaluated on BCL2, BCL6, and MYC loci
  3. (^) Response to first-line treatment was assessed in 32 patients. Four patients were not evaluable for
  4. treatment response assessment (early deaths n = 3, lost n = 1)