Fig. 7

Clinical relevance of Chibby, Wnt/β-catenin signaling and PDK1. a Representative immunostaining of Chibby, β-catenin and PDK1 in normal and NPC tissue samples. Scale bar: 100 μm. b Relative frequency of the immunoreactive scores for Chibby, β-catenin and PDK1 staining on 45 NPC tissues and 45 normal nasopharyngeal tissues. Fisher’s exact test was used for categorical variables (p < 0.001). c The correlation between Chibby and β-catenin protein levels. d The correlation between Chibby and PDK1 protein levels. e The correlation between β-catenin and PDK1 protein levels. Pearson’s correlation test was used for c to e (r and p values are shown in the graphs of c to e)