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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: TRIM52 up-regulation in hepatocellular carcinoma cells promotes proliferation, migration and invasion through the ubiquitination of PPM1A

Fig. 5

TRIM52 down-regulation inhibits HCC cell growth in vivo. After MHCC-97H cells transfected with pLKO.1-shRNA-TRIM52 or pLKO.1-scramble shRNA (NC) were subcutaneously injected into the nude mice, the tumor weight (a), volume (b) and Ki67, p-Smad2/3 and MMP2 expression (c) were measured, respectively. Scale bars: 100 μm. **P < 0.01 compared with corresponding NC

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