Fig. 2
From: Metabolic reprogramming-based characterization of circulating tumor cells in prostate cancer
Determination of optimal markers for the metabolic profiling of CTCs. a The mRNA expressions of metastasis-related glucose metabolic genes in E-CTCs, H-CTCs, and M-CTCs in patients of Cohort 1, including HK2, PDP2, G6PD, PGK1, PHKA1, PYGL, PDK1, and PKM2. The legend S indicates the example that is negative for the mRNA expression of metabolic genes. Gap1 and gap2 show the intervals between different EMT subtypes; for each part, the height of gap1 or gap2 equals one CTC. b The analytic hierarchy process (AHP)-based model for evaluating the performance of the eight metabolic genes. (i), The target layer; (ii) the criterion layer; (iii) the scheme layer; (iv) the weighting coefficients determined by pairwise comparison matrix; and (v) the weighted calculation model of performance scores