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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Metabolic reprogramming-based characterization of circulating tumor cells in prostate cancer

Fig. 4

Correlation between the metabolic and EMT phenotypes of CTCs. ac Correlation between the numbers of GM+CTCs and the EMT phenotypes, including E-CTCs (a), H-CTCs (b), and M-CTCs (c). d Images of multi-fluorescence signals representing the EMT markers (E markers: EpCAM and CK8/18/19; M markers: Vimentin and Twist) and glucose metabolic markers (GM markers: PGK1 and G6PD). The merged image shows the GM+ and GM subtypes of E-CTCs, H-CTCs, and M-CTCs, respectively. Scale bar = 5 μm. e The metabolic subtypes of total E-CTCs, H-CTCs, and M-CTCs

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