Fig. 1

Elevated expression of COPS3 in lung metastasis of osteosarcoma. a COPS3 expression in 18 pairs of primary osteosarcoma tissues and matched lung metastasis tissues was evaluated by immunohistochemistry. b IHC scores of COPS3 staining in primary osteosarcoma and matched lung metastasis tissues were analyzed by Wilcoxon signed-rank test. **P < 0.01 vs. the primary tumor group. Scale bars: 100 μm