Fig. 1
The scar tissue in the CCP-treated and rescued mice harbors activated natural killer (NK) cells: possible CCP-induced recruitment of activated NK cells. Brain sections harboring the tumor (Vehicle-treated) and Scar tissue (CCP-treated and rescued) were analyzed by IHC using the activated NK cell-specific NKp46 antibody. a and b The Vehicle-treated tumor tissue display very little NKp46 stain, the scar tissue sections derived from the CCP-treated and rescued mice show an 800% increase in NKp46-staining (mean ± S.D.). Three sections per mouse were used for IHC and the data (mean ± S.D.) obtained from Vehicle-treated (n = 4) and CCP-treated and rescued (n = 4) (Scale bar: 47.62 μm)