Fig. 6From: PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesisA schematic model of the role and underlying mechanism of PTEN lipid phosphatase inactivation in GC development. PTEN lipid phosphatase inactivation negatively regulates the Hippo signaling pathway and activates the PI3K/Akt signaling pathway, leading to enhanced GC proliferation and migration and resulting in gastric tumorigenesis and developmentBack to article page