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Table 2 Correlation of YAP protein expression with clinicopathologic features in GC patients

From: PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis

Variables YAP expression
All cases (n = 90) Low expression (n = 37) High expression (n = 53) p value High nuclear expression (n = 25) Low nuclear expression (n = 65) p value High cytoplasmic expression (n = 21) Low cytoplasmic expression (n = 69) p value
Sex
 Male 53 22 31 0.927 15 38 0.894 13 40 0.748
 Female 37 15 22 10 27 8 29
Age (years)
  ≥ 63 46 19 27 0.970 12 34 0.714 11 35 0.894
  < 63 44 18 26 13 31 10 34
Tumor size (cm)
  ≥ 5.5 42 12 30 0.024 16 26 0.041 11 31 0.549
  < 5.5 48 25 23 9 39 10 38
Location
 Upper 1/3 10 3 7 0.424 3 7 0.492 3 7 0.518
 Middle 27 11 16 10 17 4 23
 Low 1/3 51 22 29 12 39 13 38
 Remnant 2 1 1 0 2 1 1
T classification
 T1 3 3 0 0.040 0 3 0.003 0 3 0.708
 T2 11 5 6 3 8 2 9
 T3 53 24 29 9 44 14 39
 T4 23 5 18 13 10 5 18
N classification
 N0 22 17 5 0.000 1 21 0.005 4 18 0.511
 N1/N2/N3 68 20 48 24 44 17 51
Clinical stage
 I/II 36 27 9 0.000 2 34 0.000 6 30 0.222
 III/IV 54 10 44 23 31 15 39