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Table 3 Summary of univariate and multivariate Cox regression analysis of overall survival duration

From: PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis

Parameter Case number p HR 95% CI
Univariate analysis
 Sex (Male vs. Female) 53/37 0.149 0.67 0.39–1.15
 Age (≥63 vs. < 63) 46/44 0.0673 0.61 0.36–1.04
 Tumor size (≥5.5 vs. < 5.5) 42/48 0.1179 1.527 0.90–2.60
 Location (Upper vs. Middle vs. Low vs. Remnant) 10/27/51/2 0.3653
 T classification (T1/T2 vs. T3/T4) 14/76 0.0031 0.39 0.21–0.73
 N classification (No vs. N1/N2/N3) 22/68 < 0.0001 0.26 0.15–0.45
 YAP (Low vs. High) 37/53 < 0.0001 0.23 0.14–0.40
 YAP (Nuclear high vs. Nuclear low) 25/65 < 0.0001 0.17 0.09–0.35
 YAP (Cytoplasm high vs. Cytoplasm low) 69/21 0.4020 0.77 0.41–1.43
 p-PTEN (Score: 0 vs. 1 vs. 2 vs. 3 vs. 4 vs. 5 vs. 6) 10/5/31/36/6/0/2 < 0.0001
Multivariate analysis
 T classification (T1/T2 vs. T3/T4) 14/76 0.043 2.92 1.03–8.28
 N classification (No vs. N1/N2/N3) 22/68 0.004 4.66 1.61–13.46
 YAP (Low vs. High) 37/53 0.001 3.70 1.70–8.04
 YAP (Nuclear high vs. Nuclear low) 25/65 0.028 1.98 1.07–3.63
 p-PTEN (Score: 0 vs. 1 vs. 2 vs. 3 vs. 4 vs. 5 vs. 6) 10/5/31/36/6/0/2 0.045 0.80 0.65–1.00