Fig. 4

MiR-498 inhibits gastric cancer proliferation, migration and invasion. a The efficiency for miR-498 transfection in GC cells was verified by qRT-PCR. b The growth of miR-498 overexpressing GC cells was determined by using cell counting assay. c Cell colony formation assays for the proliferating ability of miR-498 overexpressing GC cells. d The cell cycle distribution in miR-498 overexpressing GC cells was determined by using flow cytometry. e Flow cytometric analyses of cell apoptosis in miR-498 overexpressing GC cells. f The effects of miR-498 overexpression on the migration of GC cells were determined by using transwell migration assay. g Matrigel invasion assay was performed to determine the effects of miR-498 overexpression on GC cell invasion. h The effects of miR-498 overexpression on the expression of growth and metastasis-related genes. i The effects of miR-498 overexpression on the expression of growth and metastasis-related proteins in GC cells