Fig. 5
From: Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4
MAP4K4 is upregulated in PDAC tissues and cell lines. a MAP4K4 mRNA expression in 178 PDAC samples obtained from TCGA was shown. b, c Overexpression of MAP4K4 was associated with poorer prognosis of PDAC. d-f Higher expression of MAP4K4 was found in PDAC tissues than that in non-cancerous tissues based on GEO (GSE62452, GSE15471, GSE62165). g Higher expression of MAP4K4 was observed in PDAC tissues by qRT-PCR. h MAP4K4 protein level was detected using western blot in eight paired of PDAC tissues. i The expression of MAP4K4 in different PDAC cell lines was shown. *P < 0.05, **P < 0.01, ***P < 0.001. The data expressed as the mean ± SD. All experiments were repeated at least three times