Fig. 7
From: Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4
MAPK/ERK pathway is essential for miR-98-5p in PDAC. a The expression of MAPK/ERK signaling was evaluated by western blot. b MAPK/ERK signaling in MIAPACA-2/miR-98-5p-mimics cells treated with SB203580 or DMSO was measured by western blot. c, d The proliferation in PDAC cells following SB203580 treatment was detected by CCK-8 and colony formation assays. e The migration and invasion in PDAC cells following SB203580 treatment were determined by transwell. *P < 0.05, **P < 0.01. The data expressed as the mean ± SD. The data came from at least three independent experiments