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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer

Fig. 2

STK25 regulates aerobic glycolysis in CRC cells. a Changes in STK25 at the mRNA and protein levels were assessed by qRT-PCR (left panel) and western blot (right panel), respectively, under decreased glucose concentration. STK25:β-actin ratios shown under the representative blots were normalized to STK25 in LoVo cells deprived of glucose. Protein expression was normalized to β-actin. Culture media from controls and STK25-overexpressing or STK25-depleted CRC cells were analyzed to measure relative glucose uptake (b), lactate production (c), and lactate:glucose ratio (d). Data are expressed as mean ± SD. *, P < 0.05

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