Skip to main content

Table 1 Clinical characteristics and levels of miR-335-5p and Copine1 mRNA expression in NSCLC tissues

From: CPNE1 is a target of miR-335-5p and plays an important role in the pathogenesis of non-small cell lung cancer

Characteristics n = 60(%) miR-335-5p mRNA expression p value CPNE1 mRNA expression p value
high low high low
(n = 15) (n = 45) (n = 53) (n = 7)
Age
 ≤65 41 (68%) 9 32 0.432 36 5 0.851
 > 65 19 (32%) 6 13 17 2
Gender
 Male 38 (63%) 10 28 0.757 34 4 0.718
 Female 22 (37%) 5 17 19 3
Histology
 Adenocarcinoma 33 (55%) 7 26 0.479 30 3 0.661
 Squamous cell carcinoma 17 (28%) 4 13 14 3
 Others 10 (17%) 4 6 9 1
Smoking status
 Yes 33 (55%) 7 26 0.454 30 3 0.492
 No 27 (45%) 8 19 23 4
Clinical stage
 I/II 24 (40%) 4 20 0.224 21 3 0.870
 III/IV 36 (60%) 11 25 32 4
Lymph node metastasis
 No 24 (40%) 10 14 0.015 18 6 0.009
 Yes 36 (60%) 5 31 35 1
  1. Date are presented as the mean ± SE values. Unpaired t test was used for comparison between two groups, and the Kruskal-Wallis test was for comparison of three or more groups