|
Characteristics
|
n = 60(%)
|
miR-335-5p mRNA expression
|
p value
|
CPNE1 mRNA expression
|
p value
|
|---|
|
high
|
low
|
high
|
low
|
|---|
|
(n = 15)
|
(n = 45)
|
(n = 53)
|
(n = 7)
|
|---|
|
Age
|
|
≤65
|
41 (68%)
|
9
|
32
|
0.432
|
36
|
5
|
0.851
|
|
> 65
|
19 (32%)
|
6
|
13
|
17
|
2
|
|
Gender
|
|
Male
|
38 (63%)
|
10
|
28
|
0.757
|
34
|
4
|
0.718
|
|
Female
|
22 (37%)
|
5
|
17
|
19
|
3
|
|
Histology
|
|
Adenocarcinoma
|
33 (55%)
|
7
|
26
|
0.479
|
30
|
3
|
0.661
|
|
Squamous cell carcinoma
|
17 (28%)
|
4
|
13
|
14
|
3
|
|
Others
|
10 (17%)
|
4
|
6
|
9
|
1
|
|
Smoking status
|
|
Yes
|
33 (55%)
|
7
|
26
|
0.454
|
30
|
3
|
0.492
|
|
No
|
27 (45%)
|
8
|
19
|
23
|
4
|
|
Clinical stage
|
|
I/II
|
24 (40%)
|
4
|
20
|
0.224
|
21
|
3
|
0.870
|
|
III/IV
|
36 (60%)
|
11
|
25
|
32
|
4
|
|
Lymph node metastasis
|
|
No
|
24 (40%)
|
10
|
14
|
0.015
|
18
|
6
|
0.009
|
|
Yes
|
36 (60%)
|
5
|
31
|
35
|
1
|
- Date are presented as the mean ± SE values. Unpaired t test was used for comparison between two groups, and the Kruskal-Wallis test was for comparison of three or more groups
