Skip to main content
Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Exosomal miR-9 inhibits angiogenesis by targeting MDK and regulating PDK/AKT pathway in nasopharyngeal carcinoma

Fig. 3

Exogenous miR-9 inhibited recipient HUVEC cell migration and tube formation. Exosomes were extracted from the medium of 5-8F/con or 5-8F/miR-9 cells and co-cultured with HUVECs. Then cell migration was measured by Transwell migration assay as shown in (a). Representative pictures of transwell migration (Left) were taken at 16 h postplating and quantified for migratory cells (Right). Tube formation of HUVECs was examined by in vitro tube formation assay as shown in (b). Representative pictures of tube formation (Left) were taken at 18 h postplating and quantified for tubule length (Right). Tube formation of HUVECs was also examined by in vivo matrigel plug assay. Representative pictures of matrigel plug were taken at 2 weeks postplating as shown in (c). Representative pictures of tube formation were shown in (d) and quantified for tubule length as shown in (e). **, P < 0.01

Back to article page