Fig. 3
From: miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop
miR-589 involves in PI3K/AKT pathway in GC. a Western blot experiments were used to analyze the expression of relevant proteins in PI3K/AKT signal pathway and LIFR after miR-589 overexpression and knockdown in MGC803 and BGC823 cells. b The downregulation of p-AKT by LY294002 were abrogated after administration of miR-589 in MGC803 and BGC823 cells. The LY294002-supressed cell migration (c) and invasion (d) were counteracted by miR-589 in MGC803 and BGC823 cells, Student’s t-test, mean ± SD, ***P < 0.001