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Table 1 The correlation between the clinical characteristics of 85 patients and the expression levels of circ-IARS or linear-IARS

From: Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis

Parameters circ-IARS linar-IARS
High Low P-value High Low P-value
(n = 42) (n = 43) /χ2 (n = 42) (n = 43) /χ2
Gender    0.529    0.750
 Male 31 35 0.396 32 34 0.101
 Female 11 8   10 9  
Age, years    0.235    0.906
  ≤ 60 20 26 1.412 23 23 0.014
  > 60 22 17   19 20  
Tumor location    0.557    0.263
 Head 32 35 0.345 31 36 1.250
 Body or tail 10 8   11 7  
Tumor size, cm    0.397    0.591
  ≤ 2 12 16 0.718 15 13 0.289
  > 2 30 27   27 30  
Neural invasion    0.595    0.595
 Yes 17 15 0.283 17 15 0.283
 No 25 28   25 28  
Duodenal invasion    0.715    0.778
 Yes 6 5 0.133 5 6 0.079
 No 36 38   37 37  
Differentiation    a0.410    1.000
 Low 11 9 2.119 10 10 0.096
 Median 29 28   28 29  
 High 2 6   4 4  
Lymphatic invasion    0.058    0.058
 Yes 19 11 3.595 19 11 3.595
 No 23 32   23 32  
Vascular invasion    0.020    0.901
 Yes 15 6 5.409 12 9 0.015
 No 27 37   30 24  
Liver metastasis    a 0.011    0.481
 Yes 10 2 6.432 8 4 0.496
 No 32 41   34 39  
TNM    0.023    0.065
 I, IIa 18 29 5.195 19 28 3.396
 IIb, III and IV 24 14   23 15  
  1. aThere are at least 1 lattice theoretical frequencies less than 5, so the Fisher exact test is adopted (Monte Carlo test)
  2. Bold value indicates that its P-value less than 0.05