Fig. 5

TRIM3 overexpression inhibits gastric cancer growth and metastasis in vivo. a, The weight and volumes of tumors in control and TRIM3 overexpression groups. ((a). TRIM3-Vector; (b), TRIM3 overexpression). *P < 0.05, ** P < 0.01. b, The expression of TRIM3 and PCNA in subcutaneous tumor tissues was examined by using immunohistochemistry. Magnification, 200× (left panel); 400× (right panel). c, The number of metastatic tumor nodes in control and TRIM3 overexpression groups. **P < 0.01. d, The expression of TRIM3 and EMT associated proteins in the metastatic tumor nodes was detected by using immunohistochemistry. Magnification, 200× (left panel); 400× (right panel). e, The weight and volume of tumors in control and TRIM3-siRNA groups. *P < 0.01; **P < 0.05. f, The expression of TRIM3 and PCNA in subcutaneous tumor tissues was detected by using immunohistochemistry. Magnification, 200× (left panel); 400× (right panel). g, The number of metastatic tumor nodes in control and TRIM3-siRNA groups. *P < 0.05. h, The expression of TRIM3 and EMT associated proteins in the metastatic tumor nodes was detected by using immunohistochemistry. Magnification, 200× (left panel); 400× (right panel)