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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Exosomal TRIM3 is a novel marker and therapy target for gastric cancer

Fig. 7

Exosomal TRIM3 inhibits tumor growth and metastasis in vivo. a, The effects of TRIM3-overexpressing exosomes on tumor growth in vivo. ((a), control exosomes group; (b), TRIM3-overexpressing exosome group). *P< 0.05. b, The expression of TRIM3 and PCNA in subcutaneous tumor tissues in control exosome and TRIM3-overexpressing exosome groups. Magnification, 200× (left panel); 400× (right panel). c, The effects of TRIM3-overexpressing exosomes on tumor metastasis in vivo. The number of metastatic tumor nodes in control exosomes and TRIM3-overexpressing exosome groups were compared. *P < 0.05. d, The expression of TRIM3 and EMT associated proteins in the metastatic tumor tissues in control exosome and TRIM3-overexpressing exosome groups. Magnification, 200× (left panel); 400× (right panel)

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