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Table 2 Univariate analysis for prognostic factors affecting overall survival and disease-free survival

From: High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway

Variables OS DFS
HR 95% CI P value HR 95% CI P value
Gender
 Male vs. Female 0.883 0.477–1.633 0.691 1.029 0.600–1.767 0.916
Age
  ≤ 60 years vs. > 60 years 0.755 0.408–1.395 0.369 0.743 0.435–1.269 0.277
Tumor location
 Colon vs. Rectal 1.801 0.856–3.791 0.121 1.870 0.983–3.560 0.057
Tumor size
  ≤ 5 cm vs. > 5 cm 0.849 0.425–1.695 0.643 1.454 0.841–2.514 0.180
Tumor differentiation
 Well/moderate vs. Poor 1.071 0.525–2.187 0.850 1.014 0.533–1.929 0.967
Tumor invasion
 T1-T2 vs. T3-T4 1.394 0.585–3.321 0.454 1.610 0.726–3.567 0.241
Lymph node metastasis
 Absent vs. Present 2.298 1.194–4.424 0.013 1.759 1.016–3.048 0.044
Serum CEA level
  ≤ 5 ng/ml vs. > 5 ng/ml 1.926 1.039–3.572 0.038 2.635 1.523–4.558 0.001
RAP1A expression
 Low vs. High 2.887 1.467–5.681 0.002 2.396 1.356–4.233 0.003
  1. Italicized values are less than 0.05