Skip to main content


Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Paired box 8 suppresses tumor angiogenesis and metastasis in gastric cancer through repression of FOXM1 via induction of microRNA-612

Fig. 4

PAX8 stimulates miR-612 to downregulate FOXM1 in gastric cancer cells. a Western blot analysis of indicated proteins in AGS and SGC-7901 cells transfected with PAX8-expressing plasmid or empty vector. b Real-time PCR analysis of indicated miRs. *P < 0.05 vs. vector-transfected cells. N.S. indicates no significance. c Analysis of FOXM1 protein levels in AGS and SGC-7901 cells transfected with control miR or miR-612. d Knockdown of miR-612 prevented the inhibition of FOXM1 by PAX8, as determined by Western blot analysis

Back to article page