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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Paired box 8 suppresses tumor angiogenesis and metastasis in gastric cancer through repression of FOXM1 via induction of microRNA-612

Fig. 5

miR-612 exerts suppressive effects against gastric cancer cells. a In vitro wound-healing assay showed the suppressive effect of miR-612 on cell migration. b miR-612 overexpression significantly inhibited the invasion of both AGS and SGC-7901 cells. c Conditioned media from miR-612-overexpressing AGS and SGC-7901 cells showed a reduced angiogenic activity. d Western blot analysis of E-cadherin (E-cad) and vimentin (Vim) protein levels. *P < 0.05 vs. control miR-transfected cells

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