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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: LINC01287/miR-298/STAT3 feedback loop regulates growth and the epithelial-to-mesenchymal transition phenotype in hepatocellular carcinoma cells

Fig. 3

LncRNA LINC01287 acted as a ceRNA to regulate miR-298 expression. a The binding sites of miR-298 on LINC01287. b The RIP assay revealed that LINC01287 and miR-298 were enriched in the same Ago2 immunoprecipitates. c MiR-298 expression was increased in sh-LINC01287 cells compared with sh-ctrl cells. d Co-transfection of miR-298 and LINC01287-Wt strongly decreased the luciferase activity, while co-transfection of miR-ctrl and LINC01287-Wt did not change the luciferase activity. Co-transfection of miR-298 and LINC01287-Mut also did not change the luciferase activity. e MiR-298 decreased LINC01287 expression, while anti-miR-298 increased LINC01287 expression

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