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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: LINC01287/miR-298/STAT3 feedback loop regulates growth and the epithelial-to-mesenchymal transition phenotype in hepatocellular carcinoma cells

Fig. 6

LINC01287 inhibition decreased tumor growth and invasion in vivo. a Compared with sh-ctrl cell-derived xenograft tumors, sh- LINC01287 cell-derived xenograft tumors grew more slowly, while anti-miR-298 treatment partly abolished this effect. b The mean weight of sh-LINC01287 cell-derived xenograft tumors was significantly lower than that of sh-ctrl cell-derived xenograft tumors, while anti-miR-298 treatment partly abolished this effect. c The knockdown of LINC01287 significantly decreased the percentage of Ki-67-positive cells in the tumors compared with the negative control group, while anti-miR-298 treatment partly abolished this effect. d The knockdown of LINC01287 decreased lung metastasis in vivo, while anti-miR-298 treatment partly abolished this effect

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