Fig. 2

MeDIP-seq analysis of OPN knockdown in CD133+/CD44+ cells. a Normalized 5mC tag density distribution across the genebody. Each gene was normalized to 0–100%. b The heatmap of differentially methylated tiles (left) and normalized 5mC tag density distribution (right) in CD133+/CD44+ cells with SCR or shOPN from Huh7 using MeDIP-seq. c Average percentile changes in methylation in the different elements. d Distribution of methylation density within retrotransposon elements. Red lines presented median values. e KEGG and GO analyses of MeDIP-seq in CD133+/CD44+ cells with SCR or shOPN