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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44+ cancer stem cells to 5 azacytidine in hepatocellular carcinoma

Fig. 7

HCCs with high OPN are more sensitive to DNMT1 inhibitor, 5 Aza, in vitro. a The inhibition rate of 5 Aza in CD133+/CD44+ cells with EV or OPN from Hep3B and Huh7, 200×. b Immunoblot analysis of DNMT1 and OPN in the lysates from primary HCC cells. c IC50 values of three primary HCC cells. d The inhibition rate of 5 Aza in CD133+/CD44+ cells from primary HCC cells, 200×, *, p < 0.05

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