Fig. 6
From: Overexpression of the Kininogen-1 inhibits proliferation and induces apoptosis of glioma cells
Overexpressed KNG1 suppressed the activation of PI3K and Akt. a The levels of p-PI3K, PI3K, p-Akt and Akt by Western blot in U87-MG cells. The ratios of p-PI3K/PI3K (b) and p-Akt/Akt (c) were inhibited by KNG1 overexpression in U87-MG cells. d The levels of p-PI3K, PI3K, p-Akt and Akt by Western blot in SHG-44 cells. The ratios of p-PI3K/PI3K (e) and p-Akt/Akt (f) were inhibited by KNG1 overexpression in SHG-44 cells. The ns represents no significant difference; ★P < 0.05 versus control