Fig. 2
From: Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signaling
High-throughput sequencing analysis of differentially expressed miRNAs in A375 cell line treated with 7.5 μM ISL. a Top 10 upregulated and downregulated miRNAs in the ISL treated group compared with control group. b, c RT-qPCR analysis of the expression levels of miRNAs with fold change > 4. d, e RT-qPCR analysis of the expression level of miR-301b in ISL(0, 7.5, 15 μM) treated A375 cells and ISL(0, 5, 10 μM) treated A2058 cells, respectively. The data represented the mean ± SEM of three independent experiments. **P < 0.01 vs control; *P < 0.05 vs control; NS., not significant