Fig. 8From: Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signalingLRIG1 and miR-301b are negatively correlated clinically. a, b Expression of LRIG1 in primary melanoma sample and normal skin determined by GSE46517 and GSE15605 dataset from GEO database (calculated as the ratio of LRIG1 and GAPDH). c, d RT-qPCR analysis of the mRNA level of LRIG1 and miR-301b in primary melanoma samples and normal skin samples. e Correlation of LRIG1 and miR-301b in primary melanoma samples and normal skin samples. f Representative images of immunohistochemical of LRIG1 in primary melanoma samples and normal skin samples. ***P < 0.001Back to article page