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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Exosome-mediated transfer of lncRNA PART1 induces gefitinib resistance in esophageal squamous cell carcinoma via functioning as a competing endogenous RNA

Fig. 4

Extracellular lncRNA PART1 is packaged into exosomes in ESCC cells a RT-qPCR was performed to detect the expression level of lncRNA PART1 after treatment with 1 μg/mL RNase alone or combined with 0.1% Triton X100 for 30 min. *P < 0.05 compared to RNase A group. b TEM scanning showed the exosomes images released by ESCC cells. c Size distribution of exosomes were analyzed by Zetasizer. d Exosomal protein markers (CD63 and CD81) detection by Western blot from purified exosomes and exosome-depleted cell extracts. e RT-qPCR analysis of lncRNA PART1 expression in exosomal. ***P < 0.001 compared to parental cell group

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